Clinical Advisory Board

MULTIPLE SCLEROSIS


Prof Frederik Barkhof, MD, PhD

Professor of Neuroradiology, Dept of Radiology & Nuclear Medicine, VU University Medical Centre (VUmc), Amsterdam, The Netherlands & UCL institutes of Biomedical Engineering and Neurology, London, UK

Frederik Barkhof received his MD from VU University, Amsterdam (NL) in 1988 and defended his PhD thesis in 1992, for which he received the Philips Prize for Radiology (1992) and the Lucien Appel Prize for Neuroradiology (1994). Since 2001 he serves as a full Professor in Neuroradiology at the department of Radiology & Nuclear Medicine at VUmc. He is a senior staff member of the MS Center Amsterdam, and senior consultant of the Alzheimer Center, VUmc. In 2015 he was appointed as full Professor of Neuroradiology at institutes of Biomedical Engineering and Neurology at UCL in London ( UK) to translate novel imaging techniques.

Prof. Barkhof was the chairman of the Dutch Society of Neuroradiology and the MAGNIMS study group for many years. He is the Scientific Director of the Image Analysis Centre (IAC), involved in analysis of multicentre drug trials. He serves on the Editorial boards of Radiology, Brain, Multiple Sclerosis Journal, Neuroradiology and Neurology.

Prof. Barkhof’s research interests focus on childhood white matter disease, on multiple sclerosis (spinal cord MRI, grey matter, atrophy, histopathology correlations), on ageing (white matter lesions and microbleeds) and on dementia (hippocampal atrophy in Alzheimer and functional MR). He (co)authored >850 papers referenced in PubMed, has an H-factor of 102 and is listed among 3000 most influential scientists world-wide by Thompson-Reuters. He is the author of the books “Neuroimaging in Dementia” and “Clinical applications of functional brain MRI”.

Cumulatively, he has received >25 million euro grant money from various national and international funding agencies and performed contract research for all major pharmaceutical companies with cumulative contract value of > 15 million euro. More than 30 PhD students graduated under his supervision and 2 of them have subsequently attained a full professorship.

Dr Jeremy Chataway MA, PhD, FRCP

Consultant Neurologist National Hospital for Neurology and Neurosurgery, Queen Square, University College Foundation NHS Trust and Reader in Neurology, University College London.

He is the clinical lead of the MS group at the NHNN (about 3000 patients) and was a member of the 2014 MS NICE panel. He has a particular interest in clinical trial design and was the Chief Investigator (CI) of the recently reported MS-STAT1 trial in secondary progressive MS, using high dose simvastatin; and is the CI of the currently recruiting MRC/EME MS-SMART trial, again in secondary progressive MS. He sits on the UK MS Society Grant Review Panel for Care and Services Research and UK MS Society Clinical Trials Network Steering Group; and is the Interim Clinical Director of the UCL Comprehensive Clinical Trials Unit. He is keen to facilitate both advanced trial design and implementation.

Prof Tomas Olsson, MD, PhD

Professor of Neurology, Karolinska Institute, Stockholm, Sweden

Prof. Tomas Olsson received his MD from University of Linköping, Sweden in 1977 and went on to complete his PhD in Medical Sciences in 1980. Having obtained Specialist in Clinical Neurology in 1984, he currently holds the post of Professor in Neurology at Karolinska Institute, Sweden.

He was Chairman for the Swedish expert committee for Multiple Sclerosis (1997-2002) and is now a member and co-founder of the Swedish Multiple Sclerosis society as well as a member of multiple international MS societies. Prof. Olsson is a board member and co-founder of the European school of Neuroimmunology (ESNI), member of the international scientific board of the international congress of Neuroimmunology (ISNI), executive board member of the international scientific board of the European committee for the treatment of MS (ECTRIMS) and member of the International Multiple Sclerosis Genetics Consortium (IMSGC).

Prof. Olssons’s research interests focus on neuroinflammation with focus on multiple sclerosis, genetics, immunology and life style/environmental factors. He has (co)authored 429 original papers published in peer reviewed journals and has an H-index of 82. In 1994 he won the Erik K Fernströms prize for Medical research, in 2012 the K/ F Johansens International Award, Copenhagen and in 2014 the Swedbank's Science Prize.

 

GRAVES’ DISEASE


Prof Simon Pearce MBBS, MD, FRCP

Professor of Endocrinology at Newcastle University, UK

He qualified in Medicine. Professor Pearce also undertook postgraduate education in endocrinology at the Royal Postgraduate Medical School in Hammersmith and Brigham & Women’s Hospital in Boston. Professor Pearce was first appointed Senior Lecturer in Endocrinology in 2001 at Newcastle University and became Professor in 2007.

Professor Pearce has served on the editorial boards of the Journal of Clinical Endocrinology & Metabolism (2008-2010 and 2013-2016), Endocrinology (2012-2014) and the European Thyroid Journal. He was a member of the British Thyroid Association executive committee between 2006 and 2012 and the European Thyroid Association between 2011 and 2014.

Professor Pearce’s main research area is the treatment for autoimmune thyroid disease, including thyroid eye disease and Addison’s disease. He has published about 130 papers over the last 20 years spanning molecular endocrinology, clinical trials and guideline papers.

Prof George J Kahaly, M.D., Ph.D.

JOHANNES GUTENBERG UNIVERSITY MEDICAL CENTER, Mainz 55101, Germany

Prof George J Kahaly is Professor of Medicine and Endocrinology / Metabolism and is chief of the endocrine outpatient clinic at the Johannes Gutenberg University Medical Center, Mainz, Germany.

Prof. Kahaly directs the Molecular Thyroid Research Laboratory and has authored 241 original papers and reviews, covering clinical and experimental aspects of endocrine autoimmunity, immunogenetics of thyroid and polyglandular autoimmunity, as well as cardiovascular involvement of metabolic disorders. Original papers and reviews have been published in the New England Journal of Medicine, the Journal of Autoimmunity, the Journal of Clinical Endocrinology and Metabolism, the Journal of Nuclear Medicine, Thyroid, Endocrine Reviews, Nature Reviews and Autoimmunity Reviews.

Prof. Kahaly is Editor of the Journal of Clinical Endocrinology & Metabolism, official Organ of the American Endocrine Society. In the years 2009-2012, Dr. Kahaly served as Associate Editor of the journal THYROID, official journal of the American Thyroid Association (ATA). Prof. Kahaly is also member of the Editorial Board of the European Thyroid Journal, official journal of the European Thyroid Association (ETA).

Prof. Kahaly served as Treasurer and principle officer of the Executive Committee of the ETA between 2007 and 2016. He currently serves on the Public Health Commit- tee of the ATA. In the years 2012-2015, Prof. Kahaly has been active member of the ATA Research Committee, in 2007-2011, of the ATA Finance and Audit Committee, and in 2000-2006 member of the ATA Membership and Publication Committees. Further, Prof. Kahaly is the Treasurer of the European Group on Graves’ orbitopathy, official subgroup of the ETA. In the years 2005-2011, he was member of the Executive Committee of the German Thyroid Board.

Prof Chantal Daumerie

Cliniques Universitaires St-Luc, Brussels, Belgium

Chantal Daumerie is currently professor emeritus at the Faculty of medicine of the University of Louvain (UCL) and Cliniques Universitaires Saint-Luc.

She was raised in Brussels, educated at UCL before training in Internal Medicine, in Endocrinology and Nuclear Medicine.

Ch. Daumerie obtained a research mandate of the prestigious National Fund for scientific Research to study the influence of Somatostatin on the intestinal absorption of the nutrients.

She has previously served as president of the Thyroid Belgian Club, is head of thyroidology division in Endocrinology at Cliniques Universitaires Saint-Luc in Brussels and is on the board of the European Group of Orbitopathy (EUGOGO). She is an active member of the European Thyroid Association (ETA) and American Thyroid Association (ATA).

She studied the cerebral metabolism in hypothyroidism , participated to international clinical trials ( Phase 2) and many academic studies. She is author of more than 60 peer review papers.

 

UVEITIS


Prof Andrew Dick BSc(Hons) MBBS MD FRCP FRCS FRCOphth FMedSci

Professor of Ophthalmology, Bristol Eye Hospital, Bristol, UK

Prof Andrew Dick from University of London, Charing Cross and Westiminster Medical School (BSc(hons), MBBS). Andrew undertook MRCP training prior to entering ophthalmology residency and finally lecturership with Professor John Forrester in Aberdeen Scotland to further his clinician-scientist training. He was an MRC Post Doctoral Fellow and then Senior Lecturer at University of Aberdeen until his move to University of Bristol in 2000 as Chair and Professor of Ophthalmology. In 2007 he was elected and awarded the prestigious Fellowship of the Academy of Medical Sciences.

He remains an active researcher with over 200 peer review publications and lead laboratory and clinical research groups and he is currently on the Faculty of the National Institute of Health Biomedical Research Centre at Moorfields Eye Hospital. He was instrumental in developing the infrastructure and research facilitates for the team to deliver opportunity and choice to our patients through research trials as well as ensure management of complex ocular inflammatory disease and surgical vitreoretinal disorders are evidence based are at the forefront.